There have been many high-profile criminal cases throughout history, and many of them have generated significant public debate and discussion. Some examples include:

• The O.J. Simpson murder case: In 1994, former NFL player O.J. Simpson was acquitted of the murder of his ex-wife, Nicole Brown Simpson, and her friend, Ron Goldman. Many people felt that Simpson was guilty, while others believed that he was the victim of a racially-motivated prosecution.
• The Casey Anthony murder case: In 2011, Casey Anthony was acquitted of the murder of her 2-year-old daughter, Caylee. Many people felt that Anthony was guilty, while others believed that the prosecution had not presented enough evidence to prove her guilt beyond a reasonable doubt.
• The Amanda Knox murder case: In 2007, American student Amanda Knox and her Italian boyfriend were convicted of the murder of Knox’s British roommate, Meredith Kercher, in Italy. In 2011, Knox’s conviction was overturned on appeal, and she was acquitted of the crime. However, in 2013, an Italian court re-instated the conviction and in 2015 the Italian supreme court overturned the acquittal and ordered a new trial. In 2016, the court acquitted Amanda Knox again, and her conviction was definitively confirmed.
• The Jodi Arias murder case: In 2013, Jodi Arias was convicted of the murder of her ex-boyfriend, Travis Alexander, in Arizona. The trial was highly publicized and generated significant public debate over Arias’ guilt and the death penalty.

These cases and many others like them are examples of high-profile criminal cases that have generated significant public debate and discussion. It’s important to keep in mind that the information provided by the media is not always complete or accurate, and to seek out multiple perspectives and official sources to form a well-informed opinion about any case.